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Breast Cancer Treatment Practices in Elderly Women in a Community Hospital

机译:社区医院老年妇女的乳腺癌治疗方法

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摘要

Background. Elderly women with breast cancer are considered underdiagnosed and undertreated, and this adversely affects their overall survival. Methods. A total of 393 female breast cancer patients aged 70 years and older, diagnosed within the years 1989–1999, were identified from the tumor registry of The Brooklyn Hospital Center. Comparisons between the 3 different subgroups 70–74, 75–79, and 80 years and older were made using the Pearson Chi Square test. Results. Lumpectomy was performed in 42% of all patients, while mastectomy was done in 46% of patients. Adjuvant therapy such as chemotherapy, radiation therapy, and hormonal therapy were done in 12%, 25%, and 38%, respectively. Forty-seven percent of patients with positive lymph nodes received chemotherapy. Eighty-six percent of patients who were estrogen receptor-positive received adjuvant hormonal therapy. Overall five-year survival was only 14% for the ≥80 age group, compared to that of 32% and 35% for the 70–74 and the 75–79 age groups, respectively. Conclusions. Surgery was performed in majority of these patients, about half received lumpectomy, the other half mastectomy. Adjuvant therapies were frequently excluded, with only hormonal therapy being the most commonly used. Overall five-year survival is significantly worse in patients ≥80 years with breast cancer.
机译:背景。患有乳腺癌的老年妇女被认为未得到充分诊断和治疗不足,这会对她们的整体生存产生不利影响。方法。从布鲁克林医院中心的肿瘤登记处总共鉴定出了393例女性乳腺癌患者,年龄在70岁以上,年龄在1989-1999年之间。使用Pearson卡方检验对70-74、75-79和80岁及以上的3个不同亚组进行了比较。结果。 42%的患者进行了乳房切除术,而46%的患者进行了乳房切除术。辅助疗法(如化学疗法,放射疗法和激素疗法)的使用率分别为12%,25%和38%。淋巴结阳性的患者中有47%接受了化疗。雌激素受体阳性的患者中有86%接受了激素辅助治疗。 ≥80岁年龄组的总体五年生存率仅为14%,而70-74岁年龄段和75-79岁年龄组分别为32%和35%。结论。这些患者中大多数进行手术,大约一半接受了乳房肿块切除术,另一半接受了乳房切除术。辅助治疗经常被排除在外,仅激素治疗是最常用的。 ≥80岁的乳腺癌患者的总体五年生存期显着变差。

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